We would like to invite you on Seminar of the Department III

Elzbieta Olejarczyk, PhD

will speak about: Impact of transcranial magnetic stimulation on EEG connectivity in patients with depression and schizophrenia: comparison of TMS protocols

The seminar will take place in the Hall Professor A. Morecki, Wednesday, October 9th at 11:00 am.

Abstract
The objective of this work was to study the Transcranial Magnetic Stimulation (TMS) impact on brain connectivity in patients with depression and schizophrenia using different stimulation protocols. The connectivity analysis of EEG data was performed using Directed Transfer Function and indices based on graph theory. Three TMS protocols in depression: (1) 10Hz repetitive TMS over left dorsolateral prefrontal cortex (DLPFC), (2) 1 Hz repetitive TMS over right DLPFC, and (3) intermittent theta burst TMS, as well as two protocols in schizophrenia with auditory hallucinations: (1) 1 Hz rTMS over left temporo-parietal cortex (TPC), and (2) continuous theta burst TMS (cTBS), were compared. The results suggest that DTF may be useful marker allowing for evaluation of biological effectiveness of the TMS therapy in depression and schizophrenia. The choice of appropriate protocol may have an impact on the stimulation effect. Moreover, the effect of TMS on the brain connectivity depends on threshold and frequency band as well.